Extensive clinical evaluation has been carried out on LFD tests. Evaluations from Public Health England and the University of Oxford show these tests are accurate and sensitive enough to be used in the community for screening and surveillance purposes. When levels of virus are at their highest and people are most likely to pass on COVID-19, LFDs can detect the vast majority of cases. Recent analysis by NHS Test and Trace also showed that LFDs have a specificity of at least 99.9%. This means that for every 1,000 LFD tests carried out, there is fewer than one false positive result.

To reduce the risk of false negatives, individuals who test negative are advised to continue with other vital infection prevention control measures such as wearing a mask, washing hands regularly and social distancing, To reduce the risk of false positives, individuals who test positive are advised to get a confirmatory PCR test.